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During unusual circumstances, such as the COVID-19 pandemic, the approach to managing chronic conditions like pernicious anaemia, which requires regular B12 injections, had to be adapted, potentially influencing the perception of efficacy and safety of the treatment among patients

If highly deficient in certain vitamins, injections may be received up to 3x per week.

Data from a review of patient experiences and surveys involving more than 2200 patients with B12 deficiency in the UK indicate that many patients have concerns related to healthcare quality, safety, and treatment, with nearly two-thirds of respondents reporting that their treatment is insufficient to manage symptoms

Its most common signs include a slight yellow tinge to the whites of the eyes and skin